SCHEMBL2829465

SCHEMBL2829465

C=C(C)C(=O)NC(F)CC(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.43
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21891282 0.72 TGFBR1 (0.46) TGFBR1
SCHEMBL29342172 0.68 TGFBR1 (0.41) TGFBR1POLBTDP1L3MBTL1
SCHEMBL204127 0.67 TGFBR1 (0.35) TGFBR1POLBTDP1L3MBTL1
SCHEMBL2828943 0.67 POLB (0.33) TGFBR1POLBTDP1L3MBTL1
SCHEMBL13205121 0.66 TGFBR1 (0.52) TGFBR1TDP1
SCHEMBL3990047 0.65 TGFBR1 (0.42) TGFBR1
SCHEMBL145573 0.65 TSHR (0.38)
SCHEMBL1348161 0.65 POLB (0.35) TGFBR1POLBTDP1L3MBTL1
SCHEMBL805091 0.65 TGFBR1 (0.43) TGFBR1
SCHEMBL24333197 0.65 TGFBR1 (0.50) TGFBR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9172074-B2 Nonwoven material with particle filler CARL FREUDENBERG KG (DE) 2015-10-27 US disclosed
US-20100206804-A1 NONWOVEN MATERIAL WITH PARTICLE FILLER CARL FREUDENBERG KG (DE) 2010-08-19 US disclosed