SCHEMBL2828943

SCHEMBL2828943

C=C(C)C(=O)NC(F)(F)C(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TGFBR1 P36897 1/20 0.32
RXFP1 Q9HBX9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2828712 0.73 ALDH1A1 (0.36) POLBTDP1L3MBTL1TGFBR1RXFP1
SCHEMBL2828941 0.72 POLB (0.36) POLBTDP1L3MBTL1TGFBR1RXFP1
SCHEMBL16443419 0.72 TGFBR1 (0.33) POLBTDP1L3MBTL1TGFBR1
SCHEMBL2829462 0.68 ALDH1A1 (0.32) TDP1TGFBR1
SCHEMBL2829465 0.67 TGFBR1 (0.43) POLBTDP1L3MBTL1TGFBR1
SCHEMBL829187 0.66 ALDH1A1 (0.38) TDP1TGFBR1RXFP1
SCHEMBL138082 0.66 EPHX1 (0.41) POLBTDP1TGFBR1RXFP1
SCHEMBL25685612 0.66 RXFP1 (0.37) TDP1TGFBR1RXFP1
SCHEMBL29342172 0.65 TGFBR1 (0.41) POLBTDP1L3MBTL1TGFBR1RXFP1
SCHEMBL9580899 0.65 THRB (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9172074-B2 Nonwoven material with particle filler CARL FREUDENBERG KG (DE) 2015-10-27 US disclosed
US-20100206804-A1 NONWOVEN MATERIAL WITH PARTICLE FILLER CARL FREUDENBERG KG (DE) 2010-08-19 US disclosed