Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ESRRG | P62508 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28021743 | 0.86 | BLM (0.47) | EPHX2BLMALDH1A1ESRRGSMN1; SMN2 | |
| SCHEMBL8215905 | 0.84 | SMN1; SMN2 (0.55) | BLMALDH1A1SMN1; SMN2 | |
| SCHEMBL27559394 | 0.84 | SMN1; SMN2 (0.55) | BLMALDH1A1SMN1; SMN2 | |
| SCHEMBL16892922 | 0.80 | EPHX2 (0.49) | EPHX2NR1H4EPHX1ALDH1A1ESRRG | |
| SCHEMBL10559251 | 0.79 | TP53 (0.45) | EPHX2SLC13A5NR1H4EPHX1ESRRG | |
| SCHEMBL8494644 | 0.78 | SLC13A5 (0.50) | EPHX2SLC13A5NR1H4BLMESRRG | |
| SCHEMBL5802443 | 0.78 | MMP8 (0.57) | EPHX2SLC13A5NR1H4ALDH1A1NR4A2 | |
| SCHEMBL5178059 | 0.77 | EPHX1 (0.52) | EPHX2SLC13A5NR1H4EPHX1ALDH1A1 | |
| SCHEMBL15660797 | 0.76 | FDPS (0.46) | EPHX2BLMALDH1A1ESRRG | |
| SCHEMBL10606678 | 0.75 | EPHX2 (0.41) | EPHX2SLC13A5NR1H4BLMEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109890821-A | Amino-pyrrolopyrimidine ketone compound and its application method | 艾科尔公司 | 2019-06-14 | — | — | CN | disclosed |