Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921739 | 0.80 | L3MBTL1 (0.43) | HPGDALDH1A1HTTLMNAKMT2A | |
| SCHEMBL4538878 | 0.80 | KMT2A (0.41) | NOTUMHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL1115239 | 0.77 | HPGD (0.47) | HPGDALDH1A1HTTLMNAKMT2A | |
| SCHEMBL969710 | 0.77 | HPGD (0.52) | HPGDALDH1A1HTTLMNAKMT2A | |
| SCHEMBL14825154 | 0.77 | HPGD (0.79) | NOTUMHPGDALDH1A1HTTLMNA | |
| SCHEMBL2186819 | 0.76 | POLB (0.51) | HPGDALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL19304618 | 0.76 | HPGD (0.46) | NOTUMHPGDALDH1A1HTTLMNA | |
| SCHEMBL30277860 | 0.76 | HPGD (0.73) | NOTUMHPGDALDH1A1HTTLMNA | |
| SCHEMBL1642860 | 0.76 | HPGD (0.55) | HPGDALDH1A1HTTLMNAKMT2A | |
| SCHEMBL4279383 | 0.76 | HPGD (0.73) | NOTUMHPGDALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109890821-A | Amino-pyrrolopyrimidine ketone compound and its application method | 艾科尔公司 | 2019-06-14 | — | — | CN | disclosed |