Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921739 | 0.88 | L3MBTL1 (0.43) | KMT2APOLBHPGDSIGMAR1L3MBTL1 | |
| SCHEMBL969710 | 0.84 | HPGD (0.52) | KMT2AHPGDMEN1ALDH1A1MAPK1 | |
| SCHEMBL1115239 | 0.84 | HPGD (0.47) | KMT2AHPGDMEN1ALDH1A1MAPK1 | |
| SCHEMBL1642860 | 0.83 | HPGD (0.55) | KMT2AHPGDL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL6347565 | 0.80 | HPGD (0.46) | KMT2AHPGDHSD17B10ALDH1A1EPHX1 | |
| SCHEMBL2186819 | 0.80 | POLB (0.51) | KMT2APOLBHPGDHSD17B10L3MBTL1 | |
| SCHEMBL971067 | 0.80 | HPGD (0.51) | KMT2APOLBHPGDTP53MEN1 | |
| SCHEMBL1566654 | 0.80 | SIGMAR1 (0.57) | KMT2APOLBHPGDSIGMAR1 | |
| SCHEMBL28294904 | 0.80 | NOTUM (0.55) | KMT2AHPGDMEN1ALDH1A1NOTUM | |
| SCHEMBL2579555 | 0.79 | LMNA (0.41) | POLBHPGDSIGMAR1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |