SCHEMBL28294988

SCHEMBL28294988

CCCCCCCCC(CC)SOSC(CC)CCCCCCCC

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
DNM1 Q05193 2/20 0.37
TSHR P16473 1/20 0.36
THRB P10828 1/20 0.36
OPRM1 P35372 1/20 0.36
SMPD1 P17405 3/20 0.35
GPR84 Q9NQS5 3/20 0.34
FDPS P14324 3/20 0.34
SPHK1 Q9NYA1 1/20 0.34
FFAR1 O14842 1/20 0.34
ZDHHC7 Q9NXF8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28003999 1.00 LMNA (0.38) LMNADNM1TSHRTHRBOPRM1
SCHEMBL27275500 0.98 OPRM1 (0.37) LMNADNM1TSHRTHRBOPRM1
SCHEMBL27273733 0.91 LMNA (0.41) LMNADNM1TSHRTHRBOPRM1
SCHEMBL27275128 0.86 LMNA (0.38) LMNADNM1TSHRTHRBOPRM1
SCHEMBL17024092 0.84 OPRM1 (0.37) LMNADNM1TSHRTHRBOPRM1
SCHEMBL27922137 0.83 LMNA (0.50) LMNATSHRSMPD1GPR84FDPS
SCHEMBL27584591 0.81 TSHR (0.46) LMNADNM1TSHRTHRBOPRM1
SCHEMBL27290323 0.81 OPRM1 (0.37) LMNADNM1TSHROPRM1SMPD1
SCHEMBL27270022 0.80
SCHEMBL10631775 0.78 LMNA (0.42) LMNADNM1TSHRTHRBOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109843963-A Isocyanate composition, method for producing isocyanate polymer, and isocyanate polymer 旭化成株式会社 2019-06-04 CN disclosed
CN-109803992-A The manufacturing method of isocyanate composition and isocyanate polymer 旭化成株式会社 2019-05-24 CN disclosed
CN-109790269-A Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer 旭化成株式会社 2019-05-21 CN disclosed