Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27273733 | 0.89 | LMNA (0.41) | TSHRLMNADNM1SMPD1OPRM1 | |
| SCHEMBL27275128 | 0.85 | LMNA (0.38) | TSHRLMNADNM1SMPD1OPRM1 | |
| SCHEMBL17024092 | 0.83 | OPRM1 (0.37) | TSHRLMNADNM1SMPD1OPRM1 | |
| SCHEMBL28294988 | 0.81 | LMNA (0.38) | TSHRLMNADNM1SMPD1OPRM1 | |
| SCHEMBL28003999 | 0.81 | LMNA (0.38) | TSHRLMNADNM1SMPD1OPRM1 | |
| SCHEMBL1873671 | 0.81 | TSHR (0.52) | TSHRALDH1A1TDP1LMNADNM1 | |
| SCHEMBL27275500 | 0.79 | OPRM1 (0.37) | TSHRLMNADNM1SMPD1OPRM1 | |
| SCHEMBL27922137 | 0.78 | LMNA (0.50) | TSHRALDH1A1LMNASMPD1GPR84 | |
| SCHEMBL28151786 | 0.76 | DNM1 (0.35) | TSHRALDH1A1TDP1DNM1FDPS | |
| SCHEMBL27290323 | 0.76 | OPRM1 (0.37) | TSHRLMNADNM1SLC2A1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1966492-B | Sulfoxides or sulfones grafted onto polymers | CIBA SC HOLDING AG | 2011-05-04 | — | — | CN | disclosed |
| CN-100584891-C | Sulfoxides or sulfones grafted onto polymers | CIBA SC HOLDING AG | 2010-01-27 | — | — | CN | disclosed |
| CN-100406524-C | Sulphoxides or sulphones grafted on polymers | CIBA SC HOLDING AG (CH) | 2008-07-30 | — | — | CN | disclosed |
| CN-1966584-A | Sulfoxides or sulfones grafted onto polymers | CIBA SC HOLDING AG (CH) | 2007-05-23 | — | — | CN | disclosed |
| CN-1966492-A | Sulfoxides or sulfones grafted onto polymers | CIBA SC HOLDING AG (CH) | 2007-05-23 | — | — | CN | disclosed |
| CN-1500076-A | Sulphoxides or sulphones grafted on polymers | �������⻯ѧƷ�ع�����˾ | 2004-05-26 | — | — | CN | disclosed |