Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.43 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29750323 | 0.80 | ALDH1A1 (0.54) | ALDH1A1RAB9AMAPTNPC1GAA | |
| SCHEMBL140231 | 0.76 | GAA (0.72) | ALDH1A1RAB9AMAPTNPC1GAA | |
| SCHEMBL10998702 | 0.76 | NR4A3 (0.59) | ALDH1A1RAB9AMAPTNPC1GAA | |
| SCHEMBL4191657 | 0.75 | RAB9A (0.76) | ALDH1A1RAB9AMAPTNPC1GAA | |
| SCHEMBL12826269 | 0.75 | GAA (0.57) | ALDH1A1RAB9AMAPTNPC1GAA | |
| SCHEMBL13219335 | 0.73 | GAA (0.55) | ALDH1A1RAB9AMAPTNPC1GAA | |
| SCHEMBL27968340 | 0.73 | GAA (0.51) | ALDH1A1RAB9AMAPTNPC1GAA | |
| SCHEMBL25260663 | 0.70 | MAPT (0.52) | ALDH1A1RAB9AMAPTNPC1GAA | |
| SCHEMBL29405125 | 0.70 | MAPT (0.52) | ALDH1A1RAB9AMAPTNPC1GAA | |
| SCHEMBL11003726 | 0.70 | ALDH1A1 (0.70) | ALDH1A1RAB9AMAPTNPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104045643-B | A kind of method that copper catalysis water phase prepares pyrazolo [1,5-c] quinazoline framework compound | 江西师范大学 | 2019-05-03 | — | — | CN | disclosed |