Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765022 | 0.80 | HIF1A (0.58) | GAAMAPTALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL8765028 | 0.74 | HIF1A (0.55) | MAPTALDH1A1NPSR1SMN1; SMN2HIF1A | |
| SCHEMBL27968342 | 0.73 | NPC1 (0.44) | GAAMAPTALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL4191657 | 0.73 | RAB9A (0.76) | GAAMAPTALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL28295008 | 0.73 | ALDH1A1 (0.49) | GAAMAPTALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL29750323 | 0.71 | ALDH1A1 (0.54) | GAAMAPTALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL19423236 | 0.70 | FABP3 (0.65) | MAPTTP53LMNAATMMEN1 | |
| SCHEMBL1438281 | 0.68 | NPC1 (0.54) | GAAMAPTALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL140231 | 0.68 | GAA (0.72) | GAAMAPTALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL15426090 | 0.68 | PDE10A (0.51) | GAAMAPTALDH1A1HPGDSRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103819465-A | Novel compound | MITSUBISHI TANABE PHARMA CORP | 2014-05-28 | — | — | CN | disclosed |