Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1010773 | 0.80 | MAPT (0.39) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL1761774 | 0.78 | RAB9A (0.38) | MAPTRAB9AALDH1A1KDM4EGAA | |
| SCHEMBL4404616 | 0.77 | MAPT (0.37) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL14829430 | 0.75 | MAPT (0.43) | L3MBTL1TDP1HPGDKDM1AMAPT | |
| SCHEMBL17527769 | 0.71 | L3MBTL1 (0.48) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL18526972 | 0.71 | EGFR (0.47) | L3MBTL1CYP1A2CYP2D6CYP2C19MAPT | |
| SCHEMBL4405889 | 0.70 | ALDH1A1 (0.37) | CYP1A2CYP2C19HPGDTSHRKDM1A | |
| SCHEMBL4551089 | 0.69 | KDM4E (0.41) | CYP1A2CYP2C19TDP1TSHRMAPT | |
| SCHEMBL4398114 | 0.69 | KDM4E (0.41) | L3MBTL1CYP1A2CYP2C19HPGDTSHR | |
| SCHEMBL15063563 | 0.68 | NQO1 (0.36) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110028491-A | Fibroblast growth factor receptor inhibitor | 蓝图药品公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-105658642-B | Fibroblast growth factor receptor inhibitors | 蓝图药品公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-105658642-A | Fibroblast growth factor receptor inhibitors | 蓝图药品公司 | 2016-06-08 | — | — | CN | disclosed |