SCHEMBL28295068

SCHEMBL28295068

CCN(C(C)C)C(C)C.O=P(Cl)(Cl)Cl

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
FDPS P14324 1/20 0.33
TP53 P04637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TRPM8 Q7Z2W7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19348705 0.85 FDPS (0.38) MEN1KMT2AFDPS
Phosphoric Acid SCHEMBL15388975 0.83 FDPS (0.44) MEN1KMT2AFDPS
Phosphoric Acid SCHEMBL1860638 0.83 FDPS (0.44) MEN1KMT2AFDPS
SCHEMBL7097725 0.82
SCHEMBL1746 0.82
SCHEMBL5544690 0.82 MEN1 (0.42) MEN1KMT2A
Phosphoric Acid SCHEMBL21174021 0.81 TRPM8 (0.33) MEN1KMT2AFDPSTRPM8
SCHEMBL4912357 0.79 MEN1 (0.43) MEN1KMT2A
Methylene Chloride SCHEMBL2683607 0.79 MEN1 (0.50) MEN1KMT2A
SCHEMBL6063151 0.79 MEN1 (0.43) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110028491-A Fibroblast growth factor receptor inhibitor 蓝图药品公司 2019-07-19 CN disclosed
CN-105658642-B Fibroblast growth factor receptor inhibitors 蓝图药品公司 2019-05-03 CN disclosed