Diphenylether

Diphenylether

SCHEMBL28295082

C1=CCC(C2=CC=CC2)=C1.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 8/20 0.52
TSHR P16473 1/20 0.52
NR1H2 P55055 1/20 0.41
BAX Q07812 1/20 0.41
MAOA P21397 1/20 0.41
AKR1C3 P42330 1/20 0.38
MAOB P27338 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
KDM1A O60341 1/20 0.37
CA4 P22748 1/20 0.37
NPC1 O15118 1/20 0.37
HTT P42858 2/20 0.36
PGR P06401 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
LMNA P02545 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL27953403 0.81
Biphenyl SCHEMBL27702269 0.79 ALDH1A1 (0.45) NPC1SMN1; SMN2
Diphenylether SCHEMBL9949030 0.79 LTA4H (0.48) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL27491868 0.78 LTA4H (0.46) LTA4HTSHRNR1H2BAXMAOA
Phenol SCHEMBL27305009 0.76 CA12 (0.50) LTA4HNR1H2BAXCA1CA2
Phenol SCHEMBL28157129 0.76 CA12 (0.50) LTA4HNR1H2BAXCA1CA2
SCHEMBL3187920 0.75
SCHEMBL315517 0.75
SCHEMBL27884552 0.75
SCHEMBL13093358 0.75 LTA4H (0.43) LTA4HTSHRNR1H2BAXMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110483931-A A kind of polyacrylate polymers composite material and preparation method KINGFA SCIENCE & TECHNOLOGY CO 2019-11-22 CN disclosed
CN-110294897-A A kind of hyper-branched polyester and its synthetic method and a kind of thermoplas tic resin composite and preparation method thereof 武汉金发科技有限公司 2019-10-01 CN disclosed
CN-110256660-A A kind of hyper-branched polyester and its synthetic method and a kind of thermoplastic resin composition and preparation method thereof 武汉金发科技有限公司 2019-09-20 CN disclosed
CN-110256769-A A kind of toughening agent composition and a kind of thermoplas tic resin composite and preparation method thereof 武汉金发科技有限公司 2019-09-20 CN disclosed
CN-110204835-A A kind of toughening agent composition and a kind of thermoplas tic resin composite and preparation method thereof 武汉金发科技有限公司 2019-09-06 CN disclosed
CN-110172141-A A kind of hyper-branched polyester and its synthetic method and a kind of thermoplas tic resin composite and preparation method thereof 武汉金发科技有限公司 2019-08-27 CN disclosed
CN-110041663-A A kind of TPEE composite material and preparation method and application 金发科技股份有限公司 2019-07-23 CN disclosed
CN-109971107-A A kind of poly styrene composite material and preparation method thereof 金发科技股份有限公司 2019-07-05 CN disclosed
CN-109825059-A A kind of polypropylene polyphenyleneoxidepolystyrene ternary alloy three-partalloy and preparation method thereof and a kind of application 金发科技股份有限公司 2019-05-31 CN disclosed
CN-109796742-A Polycarbonate compositions and sulfonate and phosphorus-containing compound are in the application for reducing polycarbonate smoke and heat release 金发科技股份有限公司 2019-05-24 CN disclosed
CN-109777074-A Polycarbonate compositions and polysiloxane-polycarbonate copolymer improve the application of mineral-filled polycarbonate toughness and mobility 金发科技股份有限公司 2019-05-21 CN disclosed
CN-109777073-A Polycarbonate compositions and sulfonate and phosphorus-containing compound are in the application for reducing polycarbonate smoke and heat release 金发科技股份有限公司 2019-05-21 CN disclosed