Diphenylether

Diphenylether

SCHEMBL9949030

[Fe]C1=CC=CC1.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 8/20 0.48
TSHR P16473 1/20 0.48
NR1H2 P55055 1/20 0.39
BAX Q07812 1/20 0.39
MAOA P21397 1/20 0.39
AKR1C3 P42330 1/20 0.36
MAOB P27338 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
KDM1A O60341 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
CA4 P22748 1/20 0.34
KDM4E B2RXH2 1/20 0.34
GLA P06280 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
PGR P06401 1/20 0.34
HTT P42858 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anisole SCHEMBL2460505 0.86 CA4 (0.54) LTA4HMAOBCA1CA2CA4
Benzene SCHEMBL2456086 0.82
Biphenyl SCHEMBL6315601 0.81 ALDH1A1 (0.41) SMN1; SMN2KDM4EMAPT
Biphenyl SCHEMBL2460502 0.81 ALDH1A1 (0.41) SMN1; SMN2KDM4EMAPT
Toluene SCHEMBL2461658 0.79 LMNA (0.48) TSHRSMN1; SMN2LMNA
Diphenylether SCHEMBL28295082 0.79 LTA4H (0.52) LTA4HTSHRNR1H2BAXMAOA
Naphthalene SCHEMBL2461176 0.79 CYP2A6 (0.38)
Chlorobenzene SCHEMBL27767655 0.78 TSHR (0.46) TSHR
SCHEMBL240820 0.78
O-Xylene SCHEMBL5613076 0.77 TSHR (0.46) TSHRCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102214803-B Packaging method of photoelectronic device UNIV ELECTRONIC SCIENCE & TECH 2013-07-17 CN disclosed
US-8476824-B2 Active matrix organic electroluminescent device and method of manufacture thereof UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA (CN) 2013-07-02 US disclosed
US-20120164762-A1 Active matrix organic electroluminescent device and method of manufacture thereof UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA 2012-06-28 US disclosed
CN-101104769-A Ultraviolet light solidifying composition and preparation method thereof UNIV FUDAN (CN) 2008-01-16 CN disclosed