4-Chloroaniline

4-Chloroaniline

SCHEMBL28295247

NC(N)=O.Nc1ccc(Cl)cc1.c1ccncc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.42
MEN1 O00255 6/20 0.42
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
RAB9A P51151 4/20 0.41
MAPK1 P28482 2/20 0.40
NT5E P21589 1/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
LMNA P02545 3/20 0.39
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP2D6 P10635 1/20 0.39
MAPT P10636 1/20 0.39
CHRM1 P11229 1/20 0.39
KCNA1 Q09470 1/20 0.39
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
ALOX15 P16050 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Chloroaniline SCHEMBL28179367 0.90 MAOA (0.48) KMT2AMEN1MAOAMAOBRAB9A
3-Chloroaniline SCHEMBL28293455 0.80 ALDH1A1 (0.59) KMT2AMEN1RAB9ASMN1; SMN2LMNA
4-Chloroaniline SCHEMBL27680763 0.79 MAOA (0.39) KMT2AMEN1MAOAMAOBRAB9A
Pyridine SCHEMBL28634399 0.78 MAPT (0.61) KMT2AMEN1MAOAMAOBRAB9A
Pyridine SCHEMBL22721353 0.77 PARP10 (0.53) SMN1; SMN2TSHRMAPTCYP3A4
Aminobenzoic Acid SCHEMBL5874881 0.76 NAPRT (0.58) KMT2AMEN1MAPK1CES2CES1
Pyridine SCHEMBL1070164 0.76 NAPRT (0.60) KMT2AMEN1RAB9ALMNATSHR
4-Chloroaniline SCHEMBL7836943 0.74 MEN1 (0.52) KMT2AMEN1MAOAMAOBRAB9A
Pyridine SCHEMBL8677835 0.74 CES2 (0.50) KMT2AMEN1RAB9AMAPK1NT5E
Dalfampridine SCHEMBL27592753 0.74 MAPT (0.72) KMT2AMEN1MAPK1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107216411-B One kind quaternary ammonium salt of Acetylated Chitosans containing ureas and its preparation method and application 中国科学院烟台海岸带研究所 2019-06-11 CN disclosed