Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.78 |
| ▸ | ERN1 | O75460 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TPST2 | O60704 | 2/20 | 0.38 |
| ▸ | SULT1E1 | P49888 | 2/20 | 0.38 |
| ▸ | AHR | P35869 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708656 | 0.88 | PTPN1 (1.00) | PTPN1ERN1TDP1TPST2SULT1E1 | |
| SCHEMBL15898869 | 0.75 | PTPN1 (0.47) | PTPN1ERN1TDP1MEN1POLB | |
| SCHEMBL29955707 | 0.71 | PTPN1 (0.72) | PTPN1ERN1TPST2SULT1E1MEN1 | |
| SCHEMBL17321064 | 0.71 | PTPN1 (0.50) | PTPN1AHRMEN1KMT2APDE10A | |
| SCHEMBL10910714 | 0.71 | PTPN1 (0.50) | PTPN1TPST2SULT1E1AHRMEN1 | |
| SCHEMBL15898959 | 0.70 | PTPN1 (0.78) | PTPN1ERN1TDP1POLBKMT2A | |
| SCHEMBL29956932 | 0.69 | PTPN1 (0.68) | PTPN1ERN1TPST2SULT1E1MEN1 | |
| SCHEMBL8171800 | 0.69 | PTPN1 (0.61) | PTPN1TPST2SULT1E1AHRMEN1 | |
| SCHEMBL28262152 | 0.67 | PTPN1 (0.65) | PTPN1TDP1TPST2SULT1E1MEN1 | |
| SCHEMBL11541084 | 0.67 | PTPN1 (0.58) | PTPN1TPST2SULT1E1AHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104045552-B | Medicinal compound as neuroprotective agent | 江苏先声药业有限公司 | 2019-06-11 | — | — | CN | disclosed |