Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15159825 | 0.95 | ALDH1A1 (0.46) | ALDH1A1LMNAGAAHSD11B1MAPT | |
| SCHEMBL10823807 | 0.84 | CA1 (0.43) | ALDH1A1LMNAGAAMAPTCYP2C19 | |
| SCHEMBL28293637 | 0.81 | KIF11 (0.46) | ALDH1A1MAPTCA1CA2ACHE | |
| SCHEMBL137120 | 0.79 | F2 (0.50) | ALDH1A1LMNAGAAMEN1KMT2A | |
| SCHEMBL7622406 | 0.78 | CYP1A2 (0.32) | MAPTHPGDCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6926741 | 0.78 | ALDH1A1 (0.59) | ALDH1A1LMNAGAAHSD11B1MAPT | |
| SCHEMBL5676376 | 0.78 | CA2 (0.41) | LMNASMN1; SMN2CA1CA2HTT | |
| SCHEMBL15161692 | 0.77 | KIF11 (0.54) | — | |
| SCHEMBL7878013 | 0.75 | BCL2L1 (0.31) | — | |
| SCHEMBL1683277 | 0.75 | F2 (0.50) | ALDH1A1MAPTTDP1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118812539-A | 5-Aminotriazolopyrimidine derivative and preparation method thereof | 苏州大学 | 2024-10-22 | — | — | CN | claimed |
| CN-119462384-A | Pterostilbene derivatives and their use in preparing medicine for treating and/or preventing diseases caused by oxidative stress | 常州大学 | 2025-02-18 | — | — | CN | disclosed |
| CN-118812539-A | 5-Aminotriazolopyrimidine derivative and preparation method thereof | 苏州大学 | 2024-10-22 | — | — | CN | disclosed |
| CN-118561843-A | Preparation method of N- (2- (indole-1-yl) phenyl) benzenesulfonamide compound | 青岛科技大学 | 2024-08-30 | — | — | CN | disclosed |
| CN-117924125-A | Method for preparing sulfonamide derivative through visible light catalysis without metal participation | 苏州大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-112876488-B | Spiro indoline derivative and preparation method and application thereof | 苏州大学 | 2021-12-21 | — | — | CN | disclosed |
| CN-112876488-A | Spiro indoline derivative and preparation method and application thereof | 苏州大学 | 2021-06-01 | — | — | CN | disclosed |
| CN-109776526-A | Condensed cyclic triazole-(sulfonyl) Triazenes derivative and its preparation method and use | 西南医科大学 | 2019-05-21 | — | — | CN | disclosed |