Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293268 | 0.82 | SMN1; SMN2 (0.43) | POLBCYP1A2MAPK1CYP2C19LMNA | |
| SCHEMBL28293385 | 0.80 | POLB (0.55) | POLBLMNAMAPTALDH1A1MEN1 | |
| SCHEMBL28872888 | 0.80 | KCNJ6 (0.44) | MAPK1LMNAMAPTMEN1KMT2A | |
| SCHEMBL2514163 | 0.79 | MAPK1 (0.56) | CYP1A2MAPK1CYP2C19LMNAMAPT | |
| SCHEMBL2288170 | 0.79 | MAPT (0.53) | POLBCYP1A2MAPTALDH1A1HPGD | |
| SCHEMBL28872885 | 0.77 | LMNA (0.60) | POLBLMNAMAPTALDH1A1MEN1 | |
| Phosphine SCHEMBL28064259 | 0.77 | PTGS2 (0.58) | POLBLMNAALDH1A1PTGS2MAPK14 | |
| SCHEMBL18865881 | 0.76 | POLB (0.44) | POLBCYP1A2MAPK1CYP2C19LMNA | |
| SCHEMBL27868556 | 0.76 | GAA (0.56) | POLBCYP1A2CYP2C19MAPTALDH1A1 | |
| SCHEMBL27868554 | 0.75 | MAPT (0.38) | POLBCYP1A2MAPK1CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651253-A | Cinnamic acid ester derivant and its application as nerve protection medicine | 上海医药工业研究院 | 2019-04-19 | — | — | CN | disclosed |