SCHEMBL28295544

SCHEMBL28295544

COc1ccc(-c2nc(C(=O)OCCCCO)c(C)o2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TARBP2 Q15633 7/20 0.74
PDCD4 Q53EL6 1/20 0.74
IKBKB O14920 1/20 0.48
KDM4E B2RXH2 6/20 0.46
MAPT P10636 4/20 0.46
LMNA P02545 3/20 0.46
ALDH1A1 P00352 3/20 0.46
POLB P06746 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
HSD17B10 Q99714 3/20 0.44
RECQL P46063 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ALOX15 P16050 1/20 0.44
PPARA Q07869 2/20 0.43
PPARG P37231 1/20 0.43
GAA P10253 1/20 0.41
TSHR P16473 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3535824 0.85 TARBP2 (1.00) TARBP2PDCD4IKBKBKDM4EMAPT
SCHEMBL28297243 0.80 TARBP2 (0.81) TARBP2PDCD4IKBKBKDM4EMAPT
SCHEMBL28297236 0.78 TARBP2 (0.69) TARBP2PDCD4IKBKBKDM4EMAPT
SCHEMBL28297254 0.78 TARBP2 (1.00) TARBP2PDCD4KDM4EMAPTLMNA
SCHEMBL28297253 0.78 TARBP2 (0.95) TARBP2PDCD4IKBKBKDM4EMAPT
SCHEMBL28297260 0.78 TARBP2 (0.80) TARBP2PDCD4IKBKBKDM4EMAPT
SCHEMBL6384893 0.77 TARBP2 (0.71) TARBP2PDCD4IKBKBKDM4EMAPT
SCHEMBL7905027 0.77 TARBP2 (0.67) TARBP2PDCD4KDM4EMAPTALDH1A1
SCHEMBL28297291 0.77 TARBP2 (0.57) TARBP2PDCD4IKBKBKDM4EMAPT
SCHEMBL28295532 0.76 TARBP2 (0.62) TARBP2PDCD4IKBKBKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109810071-A A kind of miRNA biosynthesis inhibitor 中国科学院成都生物研究所 2019-05-28 CN disclosed