SCHEMBL28295569

SCHEMBL28295569

CCNOC(=O)c1coc(C)n1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NLRP3 Q96P20 1/20 0.36
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
NPC1 O15118 2/20 0.34
ITGAV P06756 1/20 0.34
CYP1A2 P05177 2/20 0.34
FBP1 P09467 1/20 0.34
DAGLA Q9Y4D2 1/20 0.33
MAPT P10636 1/20 0.32
HDAC1 Q13547 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
GSK3B P49841 1/20 0.30
DYRK1A Q13627 1/20 0.30
CYP2C19 P33261 2/20 0.30
TP53 P04637 1/20 0.30
NFKB1 P19838 1/20 0.30
RAB9A P51151 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2070169 0.80 CYP1A2 (0.55) NLRP3MEN1KMT2ANPC1CYP1A2
SCHEMBL286492 0.79 DAGLA (0.43) NPC1ITGAVCYP1A2DAGLAMAPT
SCHEMBL20267830 0.75 ALDH1A1 (0.43) NLRP3MEN1KMT2ANPC1CYP1A2
SCHEMBL13631423 0.75 ITGAV (0.50) NPC1ITGAVCYP1A2MAPTHDAC1
SCHEMBL28517912 0.75 FBP1 (0.43) NLRP3MEN1KMT2ANPC1ITGAV
SCHEMBL20267535 0.73 TSHR (0.46) CYP1A2MAPTCYP2C19TP53SMN1; SMN2
SCHEMBL18214736 0.71 ALDH1A1 (0.43) MEN1KMT2ANPC1CYP1A2MAPT
SCHEMBL14844574 0.70 P2RX7 (0.49) ITGAVCYP1A2MAPTHDAC1HDAC8
SCHEMBL5270512 0.69
SCHEMBL222642 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109652166-A A kind of volatility drawing oil free of cleaning and preparation method thereof 东莞市登喜达表面处理科技有限公司 2019-04-19 CN disclosed