Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.64 |
| ▸ | CRHBP | P24387 | 1/20 | 0.64 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | CDC7 | O00311 | 1/20 | 0.57 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 11/20 | 0.52 |
| ▸ | PPARD | Q03181 | 4/20 | 0.51 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2886858 | 0.89 | MAPT (0.80) | MEN1MAPTKMT2AKDM4EHSP90AA1 | |
| SCHEMBL4769034 | 0.85 | MAPT (0.58) | MEN1MAPTKMT2AKDM4EHSP90AA1 | |
| SCHEMBL28297235 | 0.85 | CDC7 (0.59) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL28295659 | 0.84 | CDC7 (0.57) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL28295570 | 0.84 | SMN1; SMN2 (0.63) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL28295521 | 0.84 | CDC7 (0.57) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL2168235 | 0.84 | ALDH1A1 (0.70) | MEN1MAPTKMT2AKDM4EHSP90AA1 | |
| SCHEMBL28297329 | 0.81 | CDC7 (0.60) | MEN1MAPTKMT2AKDM4EHSP90AA1 | |
| SCHEMBL13046766 | 0.81 | CDC7 (0.67) | MEN1MAPTKMT2AKDM4EHSP90AA1 | |
| SCHEMBL28297249 | 0.81 | CDC7 (0.53) | MEN1MAPTKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810071-A | A kind of miRNA biosynthesis inhibitor | 中国科学院成都生物研究所 | 2019-05-28 | — | — | CN | disclosed |