SCHEMBL28295612

SCHEMBL28295612

CC(C)CCc1c[nH]c(CCC(C)C)n1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.41
NOS1 P29475 1/20 0.41
NOS2 P35228 1/20 0.41
ESR1 P03372 4/20 0.37
ESR2 Q92731 1/20 0.37
AAK1 Q2M2I8 5/20 0.35
HRH4 Q9H3N8 2/20 0.33
GPR84 Q9NQS5 1/20 0.33
HRH3 Q9Y5N1 3/20 0.31
DAO P14920 1/20 0.31
SORT1 Q99523 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5786004 0.75 ALDH1A1 (0.37) HRH4HRH3
SCHEMBL3286058 0.72 BACE1 (0.36) NOS3NOS1NOS2HRH3
SCHEMBL28518457 0.71 NOS3 (0.37) NOS3NOS1NOS2ESR1HRH4
Ammonia Solution, Strong SCHEMBL27564492 0.71 HRH4 (0.40) ESR1ESR2AAK1HRH4
SCHEMBL12775568 0.71 HRH3 (0.37) NOS3NOS1NOS2GPR84HRH3
SCHEMBL3840247 0.69 HRH3 (0.42) NOS2ESR1ESR2GPR84HRH3
Hydrochloric Acid SCHEMBL27869466 0.69 KDM4E (0.37) NOS3NOS1NOS2ESR1HRH4
Water SCHEMBL27918105 0.69 NOS3 (0.36) NOS3NOS1NOS2ESR1
SCHEMBL30443813 0.69 SLC7A5 (0.41)
SCHEMBL29022742 0.69 SLC7A5 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109704626-A The poly-carboxylic-acid cement grinding aid and preparation method thereof that Organic fluoride modifying glycol amine replaces 湖南辰砾新材料有限公司 2019-05-03 CN claimed