Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 5/20 | 0.37 |
| ▸ | PPARA | Q07869 | 4/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4248694 | 0.75 | LMNA (0.42) | ALDH1A1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL6837007 | 0.73 | CYP1A2 (0.41) | ALDH1A1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL295469 | 0.71 | ATM (0.43) | ALDH1A1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL11444760 | 0.71 | MEN1 (0.40) | ALDH1A1MEN1KMT2APPARGPPARA | |
| SCHEMBL29833611 | 0.69 | LMNA (0.47) | CYP1A2CYP2D6SMN1; SMN2HIF1ACYP2C19 | |
| SCHEMBL216782 | 0.69 | PARP10 (0.44) | ALDH1A1MEN1KMT2ACYP1A2MTNR1A | |
| SCHEMBL11723326 | 0.69 | MEN1 (0.41) | ALDH1A1MEN1KMT2ACYP1A2MTNR1A | |
| SCHEMBL4368354 | 0.69 | CYP1A2 (0.47) | CYP1A2MTNR1AMTNR1BGAACYP2C9 | |
| SCHEMBL19350804 | 0.68 | LMNA (0.41) | ALDH1A1HIF1A | |
| SCHEMBL6392893 | 0.67 | SMN1; SMN2 (0.42) | ALDH1A1MEN1KMT2ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109640989-A | Compounds for the treatment of neurogenic orthostatic hypotension | 施万生物制药研发IP有限责任公司 | 2019-04-16 | — | — | CN | disclosed |