Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 13/20 | 0.40 |
| ▸ | PPARA | Q07869 | 11/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 2/20 | 0.37 |
| ▸ | EDNRA | P25101 | 2/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037791 | 0.78 | ATM (0.47) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL1577777 | 0.78 | CYP1A2 (0.46) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL5503297 | 0.74 | EDNRB (0.44) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL28295630 | 0.73 | ALDH1A1 (0.39) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL2046224 | 0.73 | ALOX15 (0.44) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL7322928 | 0.72 | ATM (0.49) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL8695089 | 0.72 | ATM (0.45) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL28157165 | 0.72 | PARP10 (0.39) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL17847375 | 0.72 | ALOX15 (0.43) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL530392 | 0.72 | ALDH1A1 (0.42) | CYP1A2GAACYP2C9PKMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178783-B1 | DEVICE AND USE FOR INCREASING THE TRANSDERMAL PERMEATION OF MEDICAMENTS | LOHMANN THERAPIE SYST LTS (DE) | 2004-04-21 | — | — | EP | claimed |
| US-20040208918-A1 | Device for and method of increasing the transdermal permeation of drugs | KOCH ANDREAS | 2004-10-21 | — | — | US | disclosed |
| US-6756052-B1 | EFFECTS LOCALIZED INCREASE IN TEMPERATURE AND/OR BLOOD FLOW USING RUBEFACIENT AGENT | LTS LOHMANN THERAPIE-SYSTEME AG (DE) | 2004-06-29 | — | — | US | disclosed |