Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 8/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28175732 | 0.90 | PIK3CA (0.53) | PIK3CAHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL756601 | 0.87 | GRM2 (0.53) | HTR1AADRA1DADRA1AADRA1BAPP | |
| SCHEMBL30440111 | 0.85 | PIK3CA (0.64) | PIK3CAPIK3CDPIK3CBMTORPIK3CG | |
| SCHEMBL28288868 | 0.82 | MAPK14 (0.47) | PIK3CAKDM4EALDH1A1AAK1GRM4 | |
| SCHEMBL28295741 | 0.81 | TLR8 (0.51) | PIK3CAHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL28293866 | 0.81 | PIK3CA (0.46) | PIK3CAHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL16549212 | 0.81 | PIK3CA (0.48) | PIK3CAAPPPIK3CDPIK3CBMTOR | |
| SCHEMBL29287969 | 0.79 | PIK3CA (0.49) | PIK3CAHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL17833787 | 0.77 | PIK3CA (0.48) | PIK3CAHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL6660966 | 0.76 | GRM4 (0.56) | PIK3CAAAK1GRM4CCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109796403-B | Quinoline derivatives and preparation method thereof | 安徽师范大学 | 2021-09-28 | — | — | CN | disclosed |
| CN-109796403-A | Quinoline derivatives and preparation method thereof | 安徽师范大学 | 2019-05-24 | — | — | CN | disclosed |