Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 6/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.36 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27992685 | 1.00 | CHRNA7 (0.43) | CHRNA7CHRNB2CHRNA4PIM3KDM4E | |
| SCHEMBL28004551 | 1.00 | CHRNA7 (0.43) | CHRNA7CHRNB2CHRNA4PIM3KDM4E | |
| SCHEMBL29122856 | 0.83 | PIM3 (0.44) | CHRNA7CHRNB2CHRNA4PIM3GPR17 | |
| SCHEMBL31498421 | 0.77 | KIF11 (0.44) | CHRNA7CHRNB2CHRNA4KDM4EALDH1A1 | |
| SCHEMBL27916504 | 0.75 | CHRNA7 (0.42) | CHRNA7CHRNB2CHRNA4PIM3GPR17 | |
| SCHEMBL5478501 | 0.74 | GPR35 (0.41) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28198631 | 0.73 | CHRNA7 (0.52) | CHRNA7CHRNB2CHRNA4PIM3ALDH1A1 | |
| SCHEMBL5414444 | 0.73 | SRC (0.40) | CHRNA7CHRNB2CHRNA4KDM4EALDH1A1 | |
| SCHEMBL17878901 | 0.73 | SRC (0.40) | CHRNA7CHRNB2CHRNA4KDM4EALDH1A1 | |
| SCHEMBL1893401 | 0.73 | SRC (0.40) | CHRNA7CHRNB2CHRNA4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109796582-A | Three component fluorescent polymers of one kind and preparation method thereof, a kind of fluorescent optical sensor and its application | 吉林大学 | 2019-05-24 | — | — | CN | disclosed |