Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27911621 | 0.78 | PRKCZ (0.40) | HTR2BHTR2AMAPTADRA2A | |
| SCHEMBL16048484 | 0.75 | NOTUM (0.40) | MAPT | |
| SCHEMBL11528925 | 0.74 | PRKCZ (0.33) | TAAR1 | |
| SCHEMBL3462 | 0.69 | HTR2A (0.42) | HRH3TAAR1HTR2BHTR2AHTR2C | |
| SCHEMBL27720648 | 0.68 | HTR2A (0.41) | HRH3TAAR1HTR2BHTR2AHTR2C | |
| SCHEMBL27277657 | 0.68 | HTR2A (0.41) | HRH3TAAR1HTR2BHTR2AHTR2C | |
| SCHEMBL3062170 | 0.67 | AOC3 (0.69) | HRH3TAAR1AOC3BCL2L1MAPT | |
| SCHEMBL547061 | 0.67 | CYP2A6 (0.50) | MAPTL3MBTL1 | |
| SCHEMBL4743163 | 0.66 | HTR2A (0.46) | HRH3TAAR1HTR2BHTR2AHTR2C | |
| SCHEMBL11655782 | 0.66 | EDNRB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776537-A | Purinedione as WNT pathway modulators | 新加坡科技研究局 | 2019-05-21 | — | — | CN | disclosed |