Ethylene

Ethylene

SCHEMBL28295970

C=C.O=C(O)c1ccc(Cc2ccc(C(=O)O)c(C(=O)O)c2)cc1C(=O)O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KLKB1 P03952 1/20 0.64
CTSB P07858 1/20 0.64
MMP9 P14780 1/20 0.64
DNMT1 P26358 1/20 0.64
DNMT3B Q9UBC3 1/20 0.64
DNMT3L Q9UJW3 1/20 0.64
DNMT3A Q9Y6K1 1/20 0.64
ALDH1A1 P00352 4/20 0.62
CDC25B P30305 2/20 0.62
CASP6 P55212 1/20 0.62
RCE1 Q9Y256 1/20 0.62
HNF4A P41235 1/20 0.56
CFD P00746 1/20 0.53
LTC4S Q16873 1/20 0.49
KDM4E B2RXH2 2/20 0.47
PKM P14618 1/20 0.47
HSD17B10 Q99714 3/20 0.47
CDC25A P30304 1/20 0.47
PTPN1 P18031 5/20 0.46
HMGB1 P09429 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21621 0.96 KLKB1 (0.69) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL29365057 0.96 KLKB1 (0.69) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL2117125 0.93 KLKB1 (0.67) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL5553313 0.93 KLKB1 (0.67) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL4521510 0.88 HNF4A (0.73) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL6866417 0.86 KLKB1 (0.58) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL9647489 0.84 ALDH1A1 (0.65) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL7845374 0.83 KLKB1 (0.48) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL29404777 0.82 LCK (0.62) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL23103 0.82 LCK (0.62) KLKB1CTSBMMP9DNMT1DNMT3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109843534-A The manufacturing method of optical film 柯尼卡美能达株式会社 2019-06-04 CN disclosed
CN-109843533-A The manufacturing method of optical film 柯尼卡美能达株式会社 2019-06-04 CN disclosed