Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539111 | 0.84 | ALDH1A1 (0.42) | KMT2ABAZ2BBAZ2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL974535 | 0.81 | LMNA (0.44) | KMT2ABAZ2BBAZ2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3802831 | 0.81 | KMT2A (0.47) | KMT2ASMN1; SMN2ALDH1A1L3MBTL1USP2 | |
| SCHEMBL10427543 | 0.78 | KMT2A (0.41) | KMT2ASMN1; SMN2ALDH1A1L3MBTL1USP2 | |
| SCHEMBL31467458 | 0.78 | ALDH1A1 (0.44) | KMT2ASMN1; SMN2ALDH1A1L3MBTL1POLB | |
| SCHEMBL22599563 | 0.75 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL21879930 | 0.73 | CYP4F2 (0.41) | KMT2ABAZ2BBAZ2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8543937 | 0.72 | ALDH1A1 (0.42) | KMT2ASMN1; SMN2ALDH1A1L3MBTL1POLB | |
| SCHEMBL19634911 | 0.72 | KMT2A (0.45) | KMT2ASMN1; SMN2ALDH1A1L3MBTL1USP2 | |
| SCHEMBL27163405 | 0.72 | ALDH1A1 (0.39) | KMT2ASMN1; SMN2ALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106608872-B | 5- pyrazol acid amide compounds and the preparation method and application thereof | 湖南化工研究院有限公司 | 2019-04-19 | — | — | CN | disclosed |