SCHEMBL974535

SCHEMBL974535

CCOC(=O)c1c(Cl)c(CC)nn1C

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.44
RAB9A P51151 5/20 0.42
NPC1 O15118 4/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPT P10636 2/20 0.42
POLB P06746 2/20 0.42
KMT2A Q03164 3/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
ATM Q13315 2/20 0.41
KDM4E B2RXH2 1/20 0.41
BAZ2B Q9UIF8 1/20 0.37
BAZ2A Q9UIF9 1/20 0.37
CYP2C9 P11712 1/20 0.37
GFER P55789 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21879930 0.88 CYP4F2 (0.41) LMNARAB9ANPC1SMN1; SMN2ALDH1A1
SCHEMBL28021919 0.85 LMNA (0.48) LMNARAB9ANPC1SMN1; SMN2ALDH1A1
SCHEMBL8310828 0.83 KDM4E (0.58) LMNARAB9ASMN1; SMN2ALDH1A1MAPT
SCHEMBL3802831 0.83 KMT2A (0.47) LMNASMN1; SMN2ALDH1A1MAPTKMT2A
SCHEMBL28296214 0.81 KMT2A (0.40) LMNASMN1; SMN2ALDH1A1MAPTPOLB
SCHEMBL10427543 0.81 KMT2A (0.41) RAB9ANPC1SMN1; SMN2ALDH1A1MAPT
SCHEMBL9043817 0.80 LMNA (0.45) LMNARAB9ANPC1SMN1; SMN2ALDH1A1
SCHEMBL4768937 0.80 RAB9A (0.47) LMNARAB9ANPC1SMN1; SMN2ALDH1A1
SCHEMBL2447429 0.78 ALDH1A1 (0.41) LMNASMN1; SMN2ALDH1A1MAPTPOLB
SCHEMBL31667412 0.78 POLB (0.40) LMNARAB9ANPC1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114561435-B Method for preparing 4-chloro-3-ethyl-1-methylpyrazole-5-formic acid by using magnetic carbon nanotube immobilized enzyme catalysis 南京科力硕生物科技有限公司 2022-08-30 CN claimed
CN-114561435-A Method for preparing 4-chloro-3-ethyl-1-methylpyrazole-5-formic acid by using magnetic carbon nanotube immobilized enzyme catalysis 南京科力硕生物科技有限公司 2022-05-31 CN claimed
CN-106187894-A The preparation method of 1 methyl 3 ethyl 4 chlorine 5 pyrazole carboxylic acid ethyl ester 潍坊鑫诺化工有限公司 2016-12-07 CN claimed
CN-103102307-A Method for synthesizing tolfenpyrad UNIV HEILONGJIANG 2013-05-15 CN claimed
CN-116063285-B Substituted pyrimidine (thio) ester compound and application thereof 沈阳中化农药化工研发有限公司 2025-02-11 CN disclosed
CN-118359540-A Method for producing tolfenpyrad insecticide 新沂市永诚化工有限公司 2024-07-19 CN disclosed
CN-116063285-A Substituted pyrimidine (thio) ester compound and application thereof 沈阳中化农药化工研发有限公司 2023-05-05 CN disclosed
CN-114561435-B Method for preparing 4-chloro-3-ethyl-1-methylpyrazole-5-formic acid by using magnetic carbon nanotube immobilized enzyme catalysis 南京科力硕生物科技有限公司 2022-08-30 CN disclosed
CN-114561435-B Method for preparing 4-chloro-3-ethyl-1-methylpyrazole-5-formic acid by using magnetic carbon nanotube immobilized enzyme catalysis 南京科力硕生物科技有限公司 2022-08-30 CN disclosed
CN-114920734-A 5- (pyrazole-5-yl) -1,2, 4-oxadiazole substituted benzamide compounds and preparation method and application thereof 浙江工业大学 2022-08-19 CN disclosed
CN-114561435-A Method for preparing 4-chloro-3-ethyl-1-methylpyrazole-5-formic acid by using magnetic carbon nanotube immobilized enzyme catalysis 南京科力硕生物科技有限公司 2022-05-31 CN disclosed
CN-114561435-A Method for preparing 4-chloro-3-ethyl-1-methylpyrazole-5-formic acid by using magnetic carbon nanotube immobilized enzyme catalysis 南京科力硕生物科技有限公司 2022-05-31 CN disclosed
EP-2252590-A1 SUBSTITUTED SULFONIC ACID AMIDE COMPOUNDS BASF SE (DE) 2010-11-24 EP disclosed
WO-2009101082-A1 SUBSTITUTED SULFONIC ACID AMIDE COMPOUNDS BASF SE (DE) 2009-08-20 WO disclosed
US-20070010402-A1 Novel herbicides, usage thereof, novel thienopyrimidine derivatives, intermediates of the same, and process for production thereof NIHON NOHYAKU CO., LTD., (JP) 2007-01-11 US disclosed
US-20070010402-A1 Novel herbicides, usage thereof, novel thienopyrimidine derivatives, intermediates of the same, and process for production thereof NIHON NOHYAKU CO., LTD., (JP) 2007-01-11 US disclosed
US-20070010402-A1 Novel herbicides, usage thereof, novel thienopyrimidine derivatives, intermediates of the same, and process for production thereof NIHON NOHYAKU CO., LTD., (JP) 2007-01-11 US disclosed
EP-1544202-A1 NOVEL HERBICIDES, USAGE THEREOF, NOVEL THIENOPYRIMIDINE DERIVATIVES, INTERMEDIATES OF THE SAME, AND PROCESS FOR PRODUCTION THEREOF Nihon Nohyaku Co., Ltd. (JP) 2005-06-22 EP disclosed
US-4968805-A Pyrazole derivatives and insecticidal fungicidal and miticidal compositions thereof MITSUBISHI KASEI CORPORATION (JP) 1990-11-06 US disclosed
EP-0329020-A1 Pyrazole derivatives, processes for their manufacture and insecticidal, miticidal and fungicidal compositions containg the derivatives as active ingredients MITSUBISHI KASEI CORPORATION (JP) 1989-08-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070010402-A1 Novel herbicides, usage thereof, novel thienopyrimidine derivatives, intermediates of the same, and process for production thereof DDT, DPYD, DHODH LMNA 4855/4885RAB9A 4004/4885NPC1 4881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.