Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27822967 | 0.84 | PTGS2 (0.63) | MEN1KMT2APOLBTAS1R3TAS1R1 | |
| SCHEMBL20984869 | 0.80 | RAB9A (0.49) | MEN1KMT2AMAPTPOLBTAS1R3 | |
| SCHEMBL9618331 | 0.77 | PTGS2 (0.68) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL2829063 | 0.77 | PTGS2 (0.68) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL5338241 | 0.74 | RAB9A (0.58) | MEN1KMT2APOLBALDH1A1NPC1 | |
| SCHEMBL9553829 | 0.72 | MEN1 (0.56) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL4593206 | 0.71 | HDAC8 (0.46) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL4593208 | 0.71 | HDAC8 (0.46) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL20984715 | 0.71 | RAB9A (0.47) | MEN1KMT2AMAPTPOLBTAS1R3 | |
| SCHEMBL3783576 | 0.71 | KMT2A (0.60) | MEN1KMT2AMAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238131-A1 | 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL - Portela & Ca., S.A. (PT) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009084970-A1 | 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL-PORTELA & COMPANHIA, S.A. (PT) | 2009-07-09 | — | — | WO | disclosed |