Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | CFD | P00746 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19926267 | 0.81 | ALOX5 (0.41) | HTR2AHRH1CHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL28706811 | 0.80 | ALOX5 (0.40) | HTR2AHRH1CHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL28690394 | 0.80 | ALOX5 (0.40) | HTR2AHRH1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18822219 | 0.79 | ALOX5 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4ALOX5 | |
| SCHEMBL9244730 | 0.79 | CHRNB2 (0.42) | HTR2AHRH1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3461 | 0.79 | CHRNB2 (0.42) | HTR2AHRH1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL13591893 | 0.78 | ALOX5 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4ALOX5 | |
| SCHEMBL20763599 | 0.76 | RIPK1 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4ALOX5 | |
| SCHEMBL13536755 | 0.76 | ALOX5 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4ALOX5 | |
| SCHEMBL27927012 | 0.75 | ALOX5 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843379-B | Substituted ureas and methods of making and using the same | 梅比斯发现公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-109843379-A | Substituted ureas and methods of making and using the same | 梅比斯发现公司 | 2019-06-04 | — | — | CN | disclosed |