Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SRD5A1 | P18405 | 6/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.44 |
| ▸ | PPIB | P23284 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2537515 | 0.89 | ALDH1A1 (0.71) | ALDH1A1HTTMAPTLMNAMAPK1 | |
| SCHEMBL8280402 | 0.81 | PPIB (0.50) | ALDH1A1HTTMAPTLMNAMAPK1 | |
| SCHEMBL3832407 | 0.81 | ALDH1A1 (0.77) | ALDH1A1HTTMAPTLMNAMAPK1 | |
| SCHEMBL19267926 | 0.80 | ALDH1A1 (0.60) | ALDH1A1HTTMAPTLMNAMAPK1 | |
| 1,4-Dimethoxybenzene SCHEMBL28153762 | 0.80 | CA1 (0.54) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9357880 | 0.78 | LMNA (0.57) | ALDH1A1HTTMAPTLMNASMN1; SMN2 | |
| SCHEMBL11403008 | 0.77 | PPIB (0.50) | ALDH1A1HTTMAPTLMNASMN1; SMN2 | |
| SCHEMBL12534115 | 0.76 | HSP90AA1 (0.58) | ALDH1A1HTTMAPTLMNASMN1; SMN2 | |
| SCHEMBL9732732 | 0.76 | ALDH1A1 (0.61) | ALDH1A1HTTMAPTLMNASMN1; SMN2 | |
| SCHEMBL7826854 | 0.76 | PPIB (0.49) | ALDH1A1HTTMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105307655-B | Pyridazinone compound and its be used to prepare treatment tumour shape fibrosis drug application | 弗拉特利发现实验室有限责任公司 | 2019-05-03 | — | — | CN | disclosed |