Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | AGER | Q15109 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL796628 | 0.97 | KDM4E (0.47) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL6042801 | 0.89 | PTPN1 (0.51) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL28287263 | 0.86 | IKBKB (0.47) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL286897 | 0.83 | PTPN1 (0.50) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL2276390 | 0.81 | PTPN1 (0.49) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL8881039 | 0.81 | PTPN1 (0.55) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL1138239 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL27480442 | 0.80 | PTPN1 (0.60) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL5513972 | 0.80 | LMNA (0.54) | KDM4EALDH1A1MAPTALOX15L3MBTL1 | |
| SCHEMBL126180 | 0.79 | MEN1 (0.54) | KDM4EALDH1A1MAPTALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108774220-B | For treating compound and its application of myocardial ischemia | 西安培华学院 | 2019-04-23 | — | — | CN | disclosed |