Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Propene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propene SCHEMBL8155698 | 0.88 | — | — | |
| Propene SCHEMBL14765281 | 0.88 | — | — | |
| Propene SCHEMBL28309332 | 0.88 | — | — | |
| Propene SCHEMBL28258940 | 0.88 | — | — | |
| Propene SCHEMBL10525658 | 0.88 | — | — | |
| Propene SCHEMBL8039600 | 0.87 | TSHR (0.33) | — | |
| Propene SCHEMBL4948068 | 0.87 | TSHR (0.33) | — | |
| Propene SCHEMBL8064619 | 0.87 | — | — | |
| Propene SCHEMBL342422 | 0.87 | — | — | |
| Propene SCHEMBL8431129 | 0.87 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093645-B | Polypropylene and aluminum hydroxide composite pipe and preparation method thereof | 四川兴辉腾集团有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-110698600-B | Preparation method and application of bulk flame-retardant polypropylene graft | 湖南工学院 | 2022-09-27 | — | — | CN | disclosed |
| CN-109810404-B | Polypropylene/metal hydroxide/rare earth compound flame-retardant material | 浙江大学宁波理工学院 | 2021-11-23 | — | — | CN | disclosed |
| CN-110698600-A | Preparation method and application of bulk flame-retardant polypropylene graft | 湖南工学院 | 2020-01-17 | — | — | CN | disclosed |
| CN-109810404-A | A kind of polypropylene/metal hydroxides/rare earth compound fire proofing | 浙江大学宁波理工学院 | 2019-05-28 | — | — | CN | disclosed |