Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28294951 | 0.82 | SIGMAR1 (0.41) | IDO1ADRA1AADRA1BADRA1DCOMT | |
| SCHEMBL28296688 | 0.81 | SIGMAR1 (0.36) | IDO1HRH1 | |
| SCHEMBL28294965 | 0.80 | PRKAB2 (0.38) | IDO1 | |
| SCHEMBL28296691 | 0.79 | PARP1 (0.40) | PDE9A | |
| SCHEMBL30332563 | 0.75 | IDO1 (0.58) | IDO1SCN4AUSP2LMNAHRH2 | |
| SCHEMBL28296693 | 0.74 | NPC1 (0.47) | CDK1CDK2 | |
| SCHEMBL28296689 | 0.72 | NPC1 (0.48) | CDK1CDK2 | |
| SCHEMBL28294956 | 0.72 | NPC1 (0.47) | CDK1CDK2 | |
| SCHEMBL28296687 | 0.70 | NPC1 (0.48) | CDK1CDK2 | |
| SCHEMBL28163398 | 0.68 | MAOA (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109665987-A | Naphthalene lactim-polyamines conjugate and its preparation method and application | 河南大学 | 2019-04-23 | — | — | CN | disclosed |