Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4657611 | 0.89 | GABRA1 (0.42) | TRPA1ATMGAAL3MBTL1ALDH1A1 | |
| SCHEMBL27961306 | 0.85 | ALDH1A1 (0.43) | GAAL3MBTL1ALDH1A1HPGDCYP3A4 | |
| SCHEMBL8496181 | 0.84 | TRPA1 (0.45) | TRPA1ATMGAAL3MBTL1ALDH1A1 | |
| SCHEMBL9418836 | 0.82 | TYR (0.44) | TRPA1ATMGAAL3MBTL1ALDH1A1 | |
| SCHEMBL22819913 | 0.81 | GAA (0.44) | GAAL3MBTL1ALDH1A1CYP1A2ACP3 | |
| SCHEMBL1955258 | 0.78 | KMT2A (0.42) | GAAL3MBTL1ALDH1A1HPGDCYP3A4 | |
| SCHEMBL28827495 | 0.77 | PPARG (0.40) | TRPA1ATMGAAL3MBTL1ALDH1A1 | |
| SCHEMBL13727456 | 0.77 | TRPA1 (0.38) | TRPA1ATMGAAL3MBTL1ALDH1A1 | |
| SCHEMBL30309279 | 0.74 | TRPA1 (0.52) | TRPA1ATMALDH1A1HPGDCYP3A4 | |
| SCHEMBL184407 | 0.74 | TRPA1 (0.52) | TRPA1ATMALDH1A1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109721617-B | Preparation method of tazobactam | 山东安舜制药有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-109721617-A | A kind of preparation method of Tazobactam Sodium | 齐鲁天和惠世（乐陵）制药有限公司 | 2019-05-07 | — | — | CN | disclosed |