Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.31 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL29358144 | 0.86 | NAPRT (0.69) | NAPRTTSHRTDP1MEN1KMT2A | |
| Pyridine SCHEMBL1536 | 0.86 | NAPRT (0.69) | NAPRTTSHRTDP1MEN1KMT2A | |
| Pyridine SCHEMBL27285374 | 0.83 | TSHR (0.64) | NAPRTTSHRTDP1MEN1KMT2A | |
| Pyridine SCHEMBL30472691 | 0.82 | — | — | |
| Pyridine SCHEMBL28067297 | 0.82 | NAPRT (0.90) | NAPRTTSHRTDP1MEN1KMT2A | |
| Pyridine SCHEMBL30984419 | 0.82 | TSHR (0.90) | NAPRTTSHRTDP1MEN1KMT2A | |
| Pyridine SCHEMBL1685618 | 0.82 | — | — | |
| Pyridine SCHEMBL6532110 | 0.82 | — | — | |
| Pyridine SCHEMBL28297010 | 0.82 | — | — | |
| Pyridine SCHEMBL5278800 | 0.79 | NAPRT (0.69) | NAPRTTSHRTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109803962-A | Modulators of cystic fibrosis transmembrane conductance regulator proteins, pharmaceutical compositions, methods of treatment, and methods for making the modulators | 弗特克斯药品有限公司 | 2019-05-24 | — | — | CN | disclosed |