Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL30984419 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL1685618 | 1.00 | — | — | |
| Pyridine SCHEMBL180431 | 0.95 | TSHR (1.00) | — | |
| Pyridine SCHEMBL16 | 0.95 | — | — | |
| Pyridine SCHEMBL933604 | 0.95 | TSHR (1.00) | — | |
| Benzene SCHEMBL1261317 | 0.95 | TSHR (1.00) | — | |
| Pyridine SCHEMBL1654468 | 0.95 | — | — | |
| SCHEMBL3052767 | 0.95 | TSHR (1.00) | — | |
| Benzene SCHEMBL10751789 | 0.95 | TSHR (1.00) | — | |
| Pyridine SCHEMBL9037865 | 0.95 | TSHR (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106905288-B | A kind of preparation method of vinylene carbonate | 山东永浩新材料科技有限公司 | 2019-05-31 | — | — | CN | disclosed |