Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | WNT1 | P04628 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039191 | 0.77 | MAPT (0.66) | MAPTPOLBPKMRAB9AKDM4E | |
| SCHEMBL22456590 | 0.77 | MAPT (0.66) | MAPTPOLBPKMRAB9AKDM4E | |
| SCHEMBL737318 | 0.77 | MEN1 (0.62) | CYP1A2CYP2D6MAPTPOLBPKM | |
| SCHEMBL2711024 | 0.76 | MAPT (0.58) | CYP1A2MAPTPOLBKDM4ELMNA | |
| SCHEMBL26234109 | 0.76 | MAPT (0.64) | MAPTPOLBPKMRAB9AKDM4E | |
| SCHEMBL3243091 | 0.75 | CYP1A2 (0.64) | CYP1A2CYP3A4CYP2D6CLK4MAPT | |
| SCHEMBL1958872 | 0.75 | MAPT (0.62) | MAPTPOLBPKMRAB9AKDM4E | |
| SCHEMBL29482111 | 0.75 | MAPT (0.62) | MAPTPOLBPKMRAB9AKDM4E | |
| SCHEMBL5247238 | 0.75 | RAB9A (0.70) | MAPTPOLBPKMRAB9AKDM4E | |
| SCHEMBL22455983 | 0.75 | MAPT (0.62) | MAPTPOLBPKMRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104837832-B | GDF-8 inhibitors | 里格尔药品股份有限公司 | 2019-04-26 | — | — | CN | disclosed |