Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.75 |
| ▸ | HTT | P42858 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.48 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6746327 | 0.92 | L3MBTL1 (0.65) | L3MBTL1TDP1LMNAHTTSMN1; SMN2 | |
| SCHEMBL14029074 | 0.89 | TDP1 (0.75) | L3MBTL1TDP1LMNAHTTSMN1; SMN2 | |
| SCHEMBL2473745 | 0.89 | L3MBTL1 (0.60) | L3MBTL1TDP1LMNAHTTSMN1; SMN2 | |
| SCHEMBL29930612 | 0.88 | L3MBTL1 (0.60) | L3MBTL1TDP1LMNAHTTSMN1; SMN2 | |
| SCHEMBL2064679 | 0.87 | L3MBTL1 (0.59) | L3MBTL1TDP1LMNAHTTSMN1; SMN2 | |
| SCHEMBL29870275 | 0.86 | L3MBTL1 (0.77) | L3MBTL1TDP1LMNAHTTSMN1; SMN2 | |
| SCHEMBL6882887 | 0.86 | L3MBTL1 (0.77) | L3MBTL1TDP1LMNAHTTSMN1; SMN2 | |
| SCHEMBL10880148 | 0.86 | TDP1 (0.71) | L3MBTL1TDP1LMNAHTTSMN1; SMN2 | |
| SCHEMBL22558337 | 0.86 | L3MBTL1 (0.62) | L3MBTL1TDP1LMNAHTTSMN1; SMN2 | |
| SCHEMBL2064683 | 0.86 | L3MBTL1 (0.58) | L3MBTL1TDP1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279121-B | The salt and crystal form or amorphous article, preparation method, pharmaceutical composition and purposes containing them of a kind of compound | 杭州普晒医药科技有限公司 | 2019-05-24 | — | — | CN | disclosed |