Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21787328 | 0.78 | TDP1 (0.46) | TDP1CA9ALDH1A1TSHRHSD17B10 | |
| SCHEMBL6255896 | 0.78 | MAPT (0.39) | TDP1CA12CA9ALDH1A1HSD17B10 | |
| SCHEMBL3952756 | 0.78 | CA1 (0.46) | TDP1CA12TGM2ALDH1A1CYP3A4 | |
| SCHEMBL4632504 | 0.78 | ALDH1A1 (0.46) | TDP1ALDH1A1HSD17B10ALOX15ALOX12 | |
| SCHEMBL21891545 | 0.77 | CA12 (0.47) | TDP1CA12CA9TGM2ALDH1A1 | |
| SCHEMBL22225161 | 0.77 | MMP2 (0.31) | CA12CA9TGM2 | |
| SCHEMBL10987834 | 0.75 | TYR (0.41) | ALDH1A1HSD17B10PTGS2 | |
| SCHEMBL2898716 | 0.75 | — | — | |
| SCHEMBL28296933 | 0.74 | TDP1 (0.46) | TDP1CA12CA9ALDH1A1TSHR | |
| SCHEMBL27269638 | 0.73 | TDP1 (0.50) | TDP1CA12CA9TGM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414803-B1 | PYRAZOLYLCARBOXANILIDES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2012-12-12 | — | — | EP | claimed |
| US-20040204470-A1 | Pyrazoylcarboxanilides as fungicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-10-14 | — | — | US | claimed |
| US-4235730-A | DISPERSANTS | TEXACO INC. (US) | 1980-11-25 | — | — | US | claimed |
| JP-56106600-A | — | — | None | — | — | JP | disclosed |
| US-20240109862-A1 | SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH | PFIZER INC. | 2024-04-04 | — | — | US | disclosed |
| WO-2021095091-A1 | AMINOARYL DERIVATIVE, INTERMEDIATE OF SAME, METHOD FOR PRODUCING SAID AMINOARYL DERIVATIVE, AND METHOD FOR PRODUCING SAID INTERMEDIATE | 藤本化学製品株式会社 | 2021-05-20 | — | — | WO | disclosed |
| US-10450297-B2 | Sulfonyl amide derivatives for the treatment of abnormal cell growth | PFIZER, INC. (US) | 2019-10-22 | — | — | US | disclosed |
| US-20190047979-A1 | SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH | PFIZER (US) | 2019-02-14 | — | — | US | disclosed |
| EP-1566693-B1 | Use of a Resist Composition for Immersion Exposure and Pattern Formation Method Using the Composition | FUJIFILM CORP (JP) | 2018-05-23 | — | — | EP | disclosed |
| US-20170327485-A1 | SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH | PFIZER (US) | 2017-11-16 | — | — | US | disclosed |
| US-9777202-B2 | Curable composition suitable for the bonding of plasticized PVC | SIKA TECHNOLOGY AG (CH) | 2017-10-03 | — | — | US | disclosed |
| WO-1997027236-A1 | POLY(OXYPROPYLENE/OXYETHYLENE) RANDOM POLYOLS USEFUL IN PREPARING FLEXIBLE HIGH RESILIENCE FOAM WITH REDUCED TENDENCIES TOWARD SHRINKAGE AND FOAM PREPARED THEREWITH | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1997-07-31 | — | — | WO | disclosed |
| EP-0273390-B1 | Radiation curable resin composition for use in magnetic recording media | MITSUBISHI RAYON CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| US-4963639-A | (METH)ACRYLATED POLYURETHANE | MITSUBISHI RAYON COMPANY, LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| US-4672071-A | Antihypertensive dihydropyridine compositions, optical isomers and intermediates | SYNTEX (U.S.A.) INC. (US) | 1987-06-09 | — | — | US | disclosed |
| EP-0191448-A2 | Antihypertensive dihydropyridine derivatives | SYNTEX (U.S.A.) INC. (US) | 1986-08-20 | — | — | EP | disclosed |
| US-4595690-A | Hypotensive agents | SYNTEX (U.S.A.) INC. (US) | 1986-06-17 | — | — | US | disclosed |
| JP-S56106600-A | NOVEL DETERMINING METHOD OF HYDROGEN PEROXIDE | WAKO PURE CHEM IND LTD | 1981-08-24 | — | — | JP | disclosed |
| US-4009201-A | PARTIALLY OR FULLY QUATERNIZED POLYAMINE ESTERS OF ACRYLIC ACIDS | ALCOLAC INC. (US) | 1977-02-22 | — | — | US | disclosed |
| US-3955984-A | STYRYL DYES | FUJI PHOTO FILM CO., LTD. (JA) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450297-B2 | Sulfonyl amide derivatives for the treatment of abnormal cell growth | GPR119, INSR, LYAR | TDP1 4027/4885CA12 4011/4885CA9 2755/4885 |
| US-20040204470-A1 | Pyrazoylcarboxanilides as fungicides | CYP1A1, CYP1B1, CYP2E1 | TDP1 864/4885CA12 3043/4885CA9 1775/4885 |
| US-20170327485-A1 | SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH | GPR119, INSR, LYAR | TDP1 4027/4885CA12 4011/4885CA9 2755/4885 |
| US-20190047979-A1 | SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH | GPR119, INSR, LYAR | TDP1 4027/4885CA12 4011/4885CA9 2755/4885 |
| US-20240109862-A1 | SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH | GPR119, INSR, LYAR | TDP1 4027/4885CA12 4011/4885CA9 2755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.