Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | RGS4 | P49798 | 1/20 | 0.48 |
| ▸ | RGS8 | P57771 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20133744 | 0.95 | SIGMAR1 (0.51) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL28710495 | 0.80 | PTGS2 (0.46) | MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL12944147 | 0.80 | RET (0.44) | MAPTALDH1A1MAPK1TDP1ADRA1D | |
| SCHEMBL8913255 | 0.78 | HDAC1 (0.67) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL11923385 | 0.77 | SIGMAR1 (0.79) | KMT2ALMNAMAPTALDH1A1MAPK1 | |
| SCHEMBL20129626 | 0.77 | PRMT5 (0.54) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL15858013 | 0.76 | GAA (0.54) | MEN1KMT2AMAPTALDH1A1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11213408 | 0.76 | SIGMAR1 (0.77) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL20509282 | 0.76 | HTR6 (0.49) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL4359832 | 0.75 | KDM1A (0.52) | MEN1KMT2ALMNAALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715614-A | The 6 yuan of cyclammonium or lactams replaced with urea and phenyl | 格吕伦塔尔有限公司 | 2019-05-03 | — | — | CN | disclosed |