Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28297004 | 0.87 | SIGMAR1 (0.45) | SMN1; SMN2HTTRECQLEPHX2SIGMAR1 | |
| Tert-Butyl Formate SCHEMBL28070392 | 0.83 | HRH1 (0.43) | SMN1; SMN2HTTRECQLEPHX2MAPT | |
| Tert-Butyl Formate SCHEMBL28009613 | 0.80 | SLC6A2 (0.36) | SMN1; SMN2HTTRECQLEPHX2ALDH1A1 | |
| SCHEMBL6120780 | 0.78 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTRECQLEPHX2SIGMAR1 | |
| SCHEMBL14626169 | 0.77 | RECQL (0.46) | SMN1; SMN2HTTRECQLEPHX2SIGMAR1 | |
| SCHEMBL3274096 | 0.76 | HRH3 (0.55) | SMN1; SMN2HTTRECQLEPHX2SIGMAR1 | |
| SCHEMBL736195 | 0.76 | HRH3 (0.58) | — | |
| SCHEMBL596980 | 0.75 | GPR119 (0.64) | GPR119MAPTALDH1A1LMNA | |
| SCHEMBL11044966 | 0.74 | EPHX2 (0.54) | SMN1; SMN2EPHX2SIGMAR1MAPTALDH1A1 | |
| SCHEMBL16532717 | 0.74 | SIGMAR1 (0.45) | SMN1; SMN2HTTRECQLEPHX2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-A | Chemical entities, composition and method | 润新生物公司 | 2019-06-07 | — | — | CN | disclosed |