Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KDM4B | O94953 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16237378 | 0.82 | CA2 (0.46) | CA2DAO | |
| SCHEMBL3009415 | 0.82 | DAO (0.53) | CA2DAO | |
| Hydrochloric Acid SCHEMBL28297052 | 0.81 | CA2 (0.49) | CA2PARP1 | |
| SCHEMBL17911192 | 0.77 | CA2 (0.45) | CA2CA12CA1CA9CA14 | |
| SCHEMBL22867155 | 0.73 | CA2 (0.45) | CA2CA12CA1CA9CA14 | |
| SCHEMBL8629691 | 0.71 | — | — | |
| SCHEMBL10368319 | 0.70 | CA2 (0.52) | CA2PARP1 | |
| SCHEMBL17351962 | 0.70 | PKM (0.48) | CA2CA12CA1CA9 | |
| SCHEMBL1416183 | 0.69 | CES2 (0.38) | CA2 | |
| SCHEMBL30543968 | 0.69 | HPGD (0.50) | DAOPARP1KDM4BKDM5CKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105960400-B | Sulfamoylthiophene amide derivatives and its purposes for being used to treat hepatitis B as drug | 爱尔兰詹森科学公司 | 2019-05-31 | — | — | CN | disclosed |