SCHEMBL28297439

SCHEMBL28297439

C[C@@H](N)c1cc(F)[c]c(F)c1

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.36
PDE2A O00408 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17028403 1.00 ADRB2 (0.36) ADRB2PDE2A
SCHEMBL18632352 0.79 GABRA1 (0.34)
SCHEMBL4336479 0.75 ADRB2 (0.36) ADRB2PDE2A
SCHEMBL24008886 0.74 ADRB2 (0.48) ADRB2PDE2A
SCHEMBL8638829 0.74 ADRB2 (0.48) ADRB2PDE2A
SCHEMBL1728961 0.74 IDO1 (0.42) ADRB2PDE2A
SCHEMBL557913 0.74 IDO1 (0.42) ADRB2PDE2A
SCHEMBL1004099 0.74 IDO1 (0.42) ADRB2PDE2A
SCHEMBL1662054 0.73 ADRB2 (0.35) ADRB2PDE2A
SCHEMBL1661088 0.73 ADRB2 (0.35) ADRB2PDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105980361-B For treating the 5- benzylisoquinoline derivative of cardiovascular disease 法国施维雅药厂 2019-05-21 CN claimed
CN-105980361-B For treating the 5- benzylisoquinoline derivative of cardiovascular disease 法国施维雅药厂 2019-05-21 CN disclosed