SCHEMBL8638829

SCHEMBL8638829

CC(N)c1cc(C(C)N)cc(C(C)N)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.48
LMNA P02545 2/20 0.38
ADRA2A P08913 1/20 0.38
ADRA2C P18825 1/20 0.38
HIF1A Q16665 1/20 0.38
KDM4E B2RXH2 1/20 0.38
PDE2A O00408 1/20 0.37
ALDH1A1 P00352 1/20 0.36
ADRB1 P08588 1/20 0.36
MIF P14174 1/20 0.36
HTR2A P28223 1/20 0.36
ADRA1A P35348 1/20 0.36
HTR2B P41595 1/20 0.36
DPP4 P27487 2/20 0.35
F2 P00734 1/20 0.35
GABRP O00591 2/20 0.35
GABRD O14764 2/20 0.35
GABRA1 P14867 2/20 0.35
GABRB1 P18505 2/20 0.35
GABRG2 P18507 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24008886 1.00 ADRB2 (0.48) ADRB2LMNAADRA2AADRA2CHIF1A
SCHEMBL659099 0.87 ADRB2 (0.46) ADRB2LMNAADRA2AADRA2CHIF1A
SCHEMBL27089977 0.85 ADRB2 (0.39) ADRB2LMNAADRA2AADRA2CHIF1A
SCHEMBL1748529 0.81 ALDH1A1 (0.45) ADRB2LMNAADRA2AADRA2CHIF1A
SCHEMBL4834641 0.81 ALDH1A1 (0.45) ADRB2LMNAADRA2AADRA2CHIF1A
SCHEMBL4832047 0.81 ALDH1A1 (0.45) ADRB2LMNAADRA2AADRA2CHIF1A
SCHEMBL14975715 0.81 HDAC4 (0.47) ADRB2LMNAADRA2AADRA2CHIF1A
SCHEMBL14847092 0.81 HDAC4 (0.47) ADRB2LMNAADRA2AADRA2CHIF1A
Hydrochloric Acid SCHEMBL14122255 0.79 ALDH1A1 (0.45) ADRB2LMNAADRA2AADRA2CHIF1A
SCHEMBL207149 0.79 ACHE (0.39) ADRB2LMNAADRA2AADRA2CHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370579-A1 HARDENER FOR EPOXY RESINS Sika Technology AG (CH) 2024-05-22 EP disclosed
WO-2023285189-A1 HARDENER FOR EPOXY RESINS SIKA TECHNOLOGY AG (CH) 2023-01-19 WO disclosed
EP-0856545-A1 Polyolefin polymer with high molecular weight DSM N.V. (NL) 1998-08-05 EP disclosed
EP-0856542-A1 Polyolefin polymer with good mechanical properties DSM N.V. (NL) 1998-08-05 EP disclosed
EP-0707611-B1 PROCESS FOR THE PREPARATION OF A DENDRITIC MACROMOLECULE DSM NV (NL) 1997-09-10 EP disclosed
EP-0707611-A1 PROCESS FOR THE PREPARATION OF A DENDRITIC MACROMOLECULE DSM NV (NL) 1996-04-24 EP disclosed
WO-1995002008-A1 PROCESS FOR THE PREPARATION OF A DENDRITIC MACROMOLECULE DSM N.V. (NL) 1995-01-19 WO disclosed