Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 10/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL21253115 | 1.00 | DNM1 (0.42) | DNM1TSHRALDH1A1TP53CYP3A4 | |
| Bromide SCHEMBL8402695 | 1.00 | DNM1 (0.42) | DNM1TSHRALDH1A1TP53CYP3A4 | |
| Bromide SCHEMBL21253208 | 1.00 | DNM1 (0.42) | DNM1TSHRALDH1A1TP53CYP3A4 | |
| Bromide SCHEMBL21247653 | 1.00 | DNM1 (0.42) | DNM1TSHRALDH1A1TP53CYP3A4 | |
| Bromide SCHEMBL21253076 | 1.00 | DNM1 (0.42) | DNM1TSHRALDH1A1TP53CYP3A4 | |
| SCHEMBL15310044 | 0.98 | LMNA (0.41) | DNM1TSHRLMNAHTTTHRB | |
| SCHEMBL2339806 | 0.98 | LMNA (0.41) | DNM1TSHRLMNAHTTTHRB | |
| SCHEMBL8327147 | 0.98 | LMNA (0.41) | DNM1TSHRLMNAHTTTHRB | |
| Hydrochloric Acid SCHEMBL9465437 | 0.95 | DNM1 (0.42) | DNM1TSHRRAD52LMNAHTT | |
| Hydrochloric Acid SCHEMBL21253135 | 0.95 | DNM1 (0.42) | DNM1TSHRRAD52LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117878471-B | Method for recycling positive electrode active material from waste lithium iron phosphate battery | 江西江铼新材料科技有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-106669980-B | A kind of method for separating of the microfine oxidized coal slime based on colloid bubble | 中国矿业大学 | 2019-05-10 | — | — | CN | disclosed |