Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28297934 | 0.84 | PDCD1 (0.46) | PDE4APDE4BPDE4CPDE4DCA12 | |
| SCHEMBL28297921 | 0.84 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DCA12 | |
| SCHEMBL19660003 | 0.80 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL28297923 | 0.78 | MEN1 (0.41) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL19643410 | 0.75 | MEN1 (0.41) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL30187456 | 0.75 | MEN1 (0.41) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL29395562 | 0.74 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4DCA12 | |
| SCHEMBL14484365 | 0.72 | ALDH1A1 (0.48) | ALDH1A1PGRSMN1; SMN2NPSR1 | |
| SCHEMBL29392667 | 0.71 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4DCA12 | |
| SCHEMBL29394845 | 0.71 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109863140-A | 3- oxo -2,6- diphenyl -2,3- dihydrogen dazin -4- formamide | 拜耳医药股份有限公司 | 2019-06-07 | — | — | CN | disclosed |