Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | CTSV | O60911 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31201123 | 1.00 | NPC1 (0.55) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL15060418 | 0.77 | NPC1 (0.56) | NPC1RAB9ALMNAKDM4EHPGD | |
| 2-Phenyl-1H-Indole SCHEMBL18059783 | 0.75 | NPC1 (0.81) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL17864136 | 0.74 | CDK4 (0.68) | NPC1LMNAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL17864134 | 0.74 | AHR (0.59) | LMNAKDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL31020778 | 0.73 | RAB9A (0.55) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL4891254 | 0.73 | RAB9A (0.55) | NPC1RAB9ALMNAKDM4EHPGD | |
| 2-Phenyl-1H-Indole SCHEMBL341378 | 0.71 | NPC1 (1.00) | NPC1RAB9ALMNAKDM4EHPGD | |
| 2-Phenyl-1H-Indole SCHEMBL29363616 | 0.71 | NPC1 (1.00) | NPC1RAB9ALMNAKDM4EHPGD | |
| SCHEMBL31450262 | 0.71 | KIF11 (0.56) | LMNAKDM4EHPGDHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107383029-B | That non-vinyl compound of six nitrogen of one kind and its application | 赤峰创兴丰华电子科技有限公司 | 2019-05-10 | — | — | CN | disclosed |