SCHEMBL28298151

SCHEMBL28298151

Cc1ccc(N(S(=O)(=O)CF)S(=O)(=O)N(C)C)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
MCOLN3 Q8TDD5 1/20 0.41
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
ALDH1A1 P00352 2/20 0.38
TSHR P16473 1/20 0.38
MEN1 O00255 1/20 0.37
HPGD P15428 1/20 0.37
KMT2A Q03164 1/20 0.37
LMNA P02545 3/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TP53 P04637 2/20 0.35
AGER Q15109 1/20 0.35
MAPK1 P28482 1/20 0.35
GFER P55789 1/20 0.35
MCL1 Q07820 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1087579 0.83 MAPT (0.39) MAPTMCOLN3MMP2MMP9ALDH1A1
SCHEMBL10285578 0.71 MAPT (0.61) MAPTMCOLN3MMP2MMP9ALDH1A1
SCHEMBL6376656 0.71 MAPT (0.40) MAPTMCOLN3MMP2MMP9ALDH1A1
SCHEMBL26310493 0.69 MAPT (0.47) MAPTMCOLN3ALDH1A1TSHRMEN1
SCHEMBL2295334 0.68 RORC (0.40) MAPTMCOLN3ALDH1A1TSHRMEN1
SCHEMBL1086173 0.68 TSHR (0.41) MAPTALDH1A1TSHRMEN1KMT2A
SCHEMBL25335307 0.67 HSP90AA1 (0.42) ALDH1A1TSHRKMT2AHTTNPSR1
SCHEMBL2295332 0.67 CA9 (0.42) MAPTMCOLN3ALDH1A1TSHRMEN1
SCHEMBL12994623 0.66 MAPT (0.48) MAPTMCOLN3MMP2MMP9ALDH1A1
SCHEMBL10192055 0.66 MAPT (0.59) MAPTMCOLN3ALDH1A1TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110128866-A The new dirt based on polysiloxanes controls coating system 汉伯公司 2019-08-16 CN disclosed
CN-110117464-A The new dirt based on polysiloxanes controls coating system 汉伯公司 2019-08-13 CN disclosed
CN-105143361-B Novel polysiloxane-based fouling control coating systems 汉伯公司 2019-06-04 CN disclosed